Faulty Molecular Master Switch May Contribute to AMD

NIH researchers discover that TGFβ signaling governs immune cell function in the eye.

A signaling pathway controlled by transforming growth factor beta (TGFβ) could be involved in the progression of age-related macular degeneration (AMD). Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have found that interrupting TGFβ signals to immune cells called microglia causes the cells to enter an activated, inflammatory state.… Read full story

Johnsonville, LLC Recalls Raw Ground Frozen Cheddar Cheese and Bacon Flavored Pork Patty Products Due to Possible Foreign Matter Contamination

WASHINGTON, Jan. 18, 2019 – Johnsonville, LLC, a Sheboygan Falls, Wis. establishment, is recalling approximately 48,371 pounds of raw ground pork patty products that may be contaminated with extraneous materials, specifically black rubber, the U.S. Department of Agriculture’s Food Safety and Inspection Service (FSIS) announced today.… Read full story

Perdue Foods LLC Recalls Simplysmart Organics Gluten Free Chicken Nugget Products Due to Possible Foreign Matter Contamination

WASHINGTON, Jan. 17, 2019 – Perdue Foods, LLC, a Perry, Ga. establishment, is recalling approximately 68,244 pounds of ready-to-eat chicken nugget products that may be contaminated with extraneous materials, specifically wood, the U.S. Department of Agriculture’s Food Safety and Inspection Service (FSIS) announced today.… Read full story

New Findings Reveal Surprising Role of the Cerebellum in Reward and Social Behaviors

NIH-funded study sheds new light on brain circuits related to affective and social dysfunction.

A new study in rodents has shown that the brain’s cerebellum—known to play a role in motor coordination—also helps control the brain’s reward circuitry. Researchers found a direct neural connection from the cerebellum to the ventral tegmental area (VTA) of the brain, which is an area long known to been involved in reward processing and encoding.… Read full story

NIH Researchers Rescue Photoreceptors, Prevent Blindness in Animal Models of Retinal Degeneration

Findings set stage for first clinical trial of stem cell-based therapeutic approach for AMD.

Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced “dry” form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older.… Read full story

Gut Microbes From Healthy Infants Block Milk Allergy Development in Mice

NIH-funded study links gut microbiome to food allergy.

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New research suggests that the gut microbiome may help prevent the development of cow’s milk allergy. Scientists at the University of Chicago found that gut microbes from healthy human infant donors transplanted into mice protected animals exposed to milk from experiencing allergic reactions, while gut microbes transplanted from infants allergic to milk did not.… Read full story

Clinical Trial Testing Fecal Microbiota Transplant for Recurrent Diarrheal Disease Begins

A research consortium recently began enrolling patients in a clinical trial examining whether fecal microbiota transplantation (FMT) by enema—putting stool from a healthy donor in the colon of a recipient—is safe and can prevent recurrent Clostridium difficile-associated disease (CDAD), a potentially life-threatening diarrheal illness.… Read full story

BRCA Exchange Aggregates Data on Thousands of BRCA Variants to Inform Understanding of Cancer Risk

A global resource that includes data on thousands of inherited variants in the BRCA1 and BRCA2 genes is available to the public. The BRCA Exchange was created through the BRCA Challenge, a long-term demonstration project initiated by the Global Alliance for Genomics and Health (GA4GH) to enhance sharing of BRCA1 and BRCA2 data.… Read full story

Oskri Organics Corporation Recalls Oskri Organic Sunflower Butter Lot #099, Oskri Tahini Butter Lot #193 and Thrive Sunflower Butter Lot #233 Because of Possible Health Risk

 

Oskri Organics Corporation of Lake Mills, WI is recalling Oskri Organic Sunflower Butter Lot # 099, Oskri Tahini Butter LOT # 193 and Thrive Sunflower Butter LOT # 233, because it has the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.… Read full story