Experimental Nasal Influenza Vaccine Tested in Kids, Teens

NIH-supported Phase 1 trial of potential broadly protective vaccine.

An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit (VTEU) site at Saint Louis University, Missouri.… Read full story

Daily Low-Dose Aspirin Found to Have No Effect on Healthy Life Span in Older People

Large NIH-funded study examined outcomes in United States and Australia

In a large clinical trial to determine the risks and benefits of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living (life free of dementia or persistent physical disability).… Read full story

High Blood Sugar During Pregnancy ups Risk of Mother’s Type 2 Diabetes, Child’s Obesity

Researchers followed mothers and their children 10-14 years after birth.

Mothers with elevated blood glucose during pregnancy – even if not high enough to meet the traditional definition of gestational diabetes – were significantly more likely to have developed type 2 diabetes a decade after pregnancy than their counterparts without high blood glucose.… Read full story

Longer Daily Fasting Times Improve Health and Longevity in Mice

Increasing time between meals made male mice healthier overall and live longer compared to mice who ate more frequently, according to a new study published in the Sept. 6, 2018 issue of Cell Metabolism. Scientists from the National Institute on Aging (NIA) at the National Institutes of Health, the University of Wisconsin-Madison, and the Pennington Biomedical Research Center, Baton Rouge, Louisiana, reported that health and longevity improved with increased fasting time, regardless of what the mice ate or how many calories they consumed.… Read full story

Stress Wracks Worm Nerves, Leaving Lasting Memories

Scientists stunted the puberty of male worms by starving them before they underwent sexual maturation. In a study funded by the National Institutes of Health, the scientists suggested that stress from starvation even days before sexual maturation prevented normal changes in the wiring patterns of key neuronal circuits, which caused adult male worms to act immature.… Read full story

NIH Study Broadens Understanding of High Impact Chronic Pain in the U.S.

Researchers have demonstrated that disability is as likely in the chronic pain population as it is in those with kidney failure, emphysema or stroke. This is the reality for 11 million U.S. adults with High Impact Chronic Pain (HICP), a new concept that describes those with pain lasting three months or longer and accompanied by at least one major activity restriction.… Read full story

Genetics and Pollution Drive Severity of Asthma Symptoms

Asthma patients, with a specific genetic profile, exhibit more intense symptoms following exposure to traffic pollution, according to researchers at the National Institutes of Health and collaborators. The study appeared online in Scientific Reports.

The research team made up of scientists from the National Institute of Environmental Health Sciences (NIEHS), part of NIH, and Rice University, Houston, also found that asthma patients that lack this genetic profile do not have the same sensitivity to traffic pollution and do not experience worse asthma symptoms.… Read full story